Creatine and Creatinine – The muscle booster and its decomposition product separated by UHPLC in HILIC mode

In the fight against COVID-19 pandemic, drugs already approved for treatment are also being tested for potential efficacy. In doing so, drugs from the related therapeutic application spectrum; i.e. viral infectious diseases; are not the only types being investigated.

The characteristic taste of gin is obtained by flavoring it with spice aromas, especially juniper berries and coriander, during or after the distillation process. Besides tannins and flavonoids, juniper berries also contain essential oils such as myrcene or α-pinene. See how you can analyze "Gin & Tonic".

In the search for effective therapeutics for COVID-19 patients, active ingredients that have shown treatment success against similar coronaviruses or influenza viruses are also included in studies.

Why is HPLC important for a perfect coffee pleasure or what the Maillard reaction has to do with coffee beans?

Ph. Eur. HPLC identification of Ivermectin – Another potential “Anti-SARS-CoV-2 fighter?”

The most deadly chemical substances include G-class nerve agents (such as “Soman”, “Sarin”, “Tabun”) and V-class (“VX”) nerve agents, which were developed in the 1940s and 1950s. Like the “Novichok” agents, which are currently frequently mentioned in the media and were developed some 20 years later, these are organophosphorous compounds that block acetylcholinesterase in the body.

See how HPLC analysis time of the two epimers Dexamethasone and Betamethasone can be reduced to a fifth by using a MACHEREY-NAGEL Pentafluorophenyl core-shell silica column without loss in resolution. In comparison the same separation performed on a conventional totally porous column with the same surface chemistry.