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Application Notes - Unveil all possibilities

Explore our application notes and learn more about the perfect synergy between MACHEREY-NAGEL’s automation-friendly extraction kits and Eppendorf’s state-of-the-art robotic systems. We are here to assist you in implementing customized genomic workflows that cater to your specific requirements.

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Discover the advantages of automation and explore MN’s extensive portfolio of automation solutions, including NucleoMag, NucleoSpin, and Protino. Our hands-free processing of a diverse range of samples at high throughput enables you to concentrate on other important tasks. We’re here to help you optimize your workflow and boost your productivity.

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All applications listed below are available on epBlue 40.4 - 40.9 (blue epMotion line) and epBlue 50.0 and newer (white epMotion line).

You don't see the right application note for your workflow or for your platform? The following application notes are exemplary applications and serve only for illustration. Please see the full application overview below.

Please feel free to contact us if you do not find your applications, if you require specific adaptions for your epMotion configuration, or if you require a custom solution.

Plasmid DNA Isolation

Kit / REF Platform Tested sample material Download
NucleoSpin 96 Plasmid Transfection-Grade Plus epMotion 5075 Bacterial culture Application Note
NucleoSpin 96 Plasmid Transfection-Grade epMotion 5075 Bacterial culture Application Note
NucleoSpin 96 Plasmid epMotion 5075 Bacterial culture Application Note
NucleoMag Plasmid epMotion 5075 Bacterial culture Application Note

RNA Isolation

Kit / REF Platform Tested sample material Download
NucleoSpin 8 RNA epMotion 5075 Animal tissue Application Note
NucleoSpin 96 RNA Plant and Fungi epMotion 5075 Plant and fungal Application Note

DNA Isolation

Kit / REF Platform Tested sample material Download
NucleoSpin Blood L epMotion 5075 Blood Application Note
NucleoSpin 96 cfDNA epMotion 5075 Plasma or serum Application Note
NucleoSpin 96 DNA RapidLyse epMotion 5075 Animal tissue Application Note
NucleoMag DNA FFPE epMotion 5075 FFPE tissue Application Note
NucleoMag DNA Food epMotion 5075 Food and feed Application Note
NucleoSpin 8/96 Plant II epMotion 5075 Plant material Application Note
NucleoSpin 96 DNA Stool epMotion 5075 Stool Application Note
NucleoMag DNA Microbiome epMotion 5075 Stool and soil Application Note

Viral RNA and DNA Isolation

Kit / REF Platform Tested sample material Download
NucleoMag Pathogen epMotion 5075 Plasma Application Note

Application overview for epMotion Systems silica membrane based

NucleoSpin scripts available for epMotion 5075v/vt from Eppendorf

Silica membrane based, automated DNA/RNA purification

Microbial / metagenomics
NucleoSpin Kits

NucleoSpin 8/96 RNA
NucleoSpin 96 DNA Stool



Forensic trace samples
NucleoSpin Kits

NucleoSpin 96 Trace




Protein purification
NucleoSpin Kits

Protino 96 Ni-NTA
Protino 96 Ni-IDA



Application overview for epMotion Systems magnetic bead based

NucleoMag scripts available for epMotion® 5075t/m and 5073t/m from Eppendorf

Magnetic bead based, automated DNA/RNA purification

Plasmid purification
NucleoMag Kits

NucleoMag Plasmid