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Derivatization reagents for GC, silylation, HMDS

HMDS should be used in addition of catalytic quantities of TMCS (e.g., 1 %) or as a mixture with TMCS (2 -1, v/v; SILYL-21 and SILYL-2110), because after that it is a fast and quantitative reagent for silylation. These products contain harmful substances which must be specially labeled as hazardous. For detailed information please see SDS.

Composition Hexamethyldisilazane (HMDS)
Derivatization type Silylation
Hazardous material Yes
Method Gas chromatography (GC), derivatization
Recommended application(s) Acetonitrile, Aprotic solvents, Carbon disulfide, Derivatization, Dimethylacetamide, Dimethylformamide, Organic compounds, Pyridine
Selling unit 5x10 mL, 6x50 mL
Storage temperature 2–8 °C / 36–46 °F