Viral nucleic acid isolation from water samples - COVID 19

Many researchers are now starting to use wastewater testing to monitor COVID-19 infection rates. Routine wastewater surveillance might be an efficient, non-invasive tool to detect new COVID-19 infections, however, complex wastewater samples present major challenges for testing laboratories due to the presence of inhibitory substances and potentially large sample volumes.The MACHEREY-NAGEL team would like to present options for pairing nucleic acid extraction kits capable of isolating SARS-CoV-2 viral RNA from wastewater samples with various methods for wastewater concentration in order to optimize the wastewater testing workflow.
View the extensive list of publications and references for MACHEREY-NAGEL products that have been implemented by researchers for wastewater testing.
Literature list

Challenges

Nucleic acid purification kits for wastewater samples

Please find below our available solutions for the purification of nucleic acids from wastewater.

Methods for sample concentration

To achieve maximum method sensitivity and efficient nucleic acid isolation from water samples, it is essential to concentrate viral particles prior to nucleic acid purification. There are numerous pretreatment options for concentrating wastewater samples down to a volume suitable for subsequent nucleic acid extraction procedures.
Explore several established wastewater concentration methods that are compatible with MACHEREY-NAGEL nucleic acid extraction kits.