E-Training – Chromatography
Chromatography as a powerful separation technique is widely used in quality control of drugs, in clinical research or in trace analysis of harmful substances. MACHEREY‑NAGEL’s comprehensive range of chromatography products, from sample preparation to subsequent analysis, provides the best solution for each analytical task. In the following, we present useful information and practical tips on the use and application of our products.
Applications
Application database Drug analysis EP and USP PFAS analysis SPE Vials and caps
Products
Column Protection System Crimping tools Sample vials and inserts TLC/HPTLC
Application database
For the basis of successful method development, we want to support you with our useful tool. The application database can help you finding application solutions for your analytical lab work with more than 3,000 application examples in the fields of HPLC, GC, TLC and SPE.
Column Protection System for HPLC
Unwanted sample contaminants are one of the main reasons for the reduction of HPLC column lifetime. Contaminants can clog the column as well as reduce the analytical performance of your HPLC column and therefor lead to prolonged downtimes of your HPLC system. To reduce these issues MACHEREY‑NAGEL recommends usage of our universal guard column holder – the Column Protection System – in combination with guard columns. Click on Read more to get more information or watch the video how to install the Column Protection System.
Content 1 Set(s)
Electronic crimping tools for reliable analysis results
Standardization in processes and methods is an important tool to achieve reproducible analysis results. Electronic crimping tools are ideal to apply this principle also to the sealing process of autosampler vials. Digital adjustments of the tool ensure a uniform crimp result independent from variances in human exertion of force as is the case with manual crimping tools. Click on Read more to get more information and e.g. to watch a video that demonstrates advantages and handling of battery-powered electronic crimping tools
Sample vials and inserts for volumes < 1.0 mL
Samples of smaller volumes must be fed to an autosampler in suitable microsample containers in order to provide the device with ideal conditions for automated sampling. When selecting a suitable product, safety, handling and price are important factors. Under “Read more” you will find an overview of the various options for micro inserts and microvials. You will also find our video on the subject of “Micro sampling in chromatography”.
Solid phase extraction (SPE)
Solid phase extraction (SPE) is a sample preparation technique. SPE is used in analytical chemistry to concentrate and purify samples. In order to perform solid phase extraction with SPE columns, a vacuum manifold is required. Click on Read more to get more information and e.g. to watch a video that illustrates how to set up the CHROMABOND SPE vacuum manifold.
Drug analysis according to USP and EP
Arzneimittel werden nach den offiziellen Methoden der Pharmakopöen analysiert. Zwei der wichtigsten Pharmakopöen weltweit sind die United States Pharmacopoeia (USP) und die European Pharamacopoeia (EP). In diesen Regelwerken werden auch die Möglichkeiten zur Optimierung einer Methode beschrieben. Um deren Richtigkeit zu unterstreichen haben wir einige dieser Methoden in verschiedenen Applikationsnoten selbst reproduziert. Dort beschreiben wir zudem die erfolgreiche Trennung ausgewählter Arzneimittel von Verunreinigungen und die Vorteile der Methodenoptimierung am Beispiel unserer HPLC-Säulen.
TLC / HPTLC plates and sheets
Thin layer chromatography is a very common separation technique, which either utilizes glass, aluminum or plastic supports in most cases coated with a thin layer of silica (stationary phase). A sample mixture applied on the surface of the layer can be separated in the single components by dipping the TLC plate or foil in an organic or aqueous/organic solvent (mobile phase). MACHEREY‑NAGEL is a pioneer in providing a wide range of ready-to-use precoated products for thin layer chromatography. Click on Read more for more details or watch a video that gives a short introduction of our TLC products.
PFAS analysis – the forever chemicals
Per- and polyfluoroalkyl substances (PFAS) are "forever chemicals" that are highly persistent in the environment and in the human body. Due to their chemical properties, they have been widely used in many different industries. Exposure to PFASs has been associated with potentially adverse health effects over time. Since the early 2000s, regulations, policies, and laws have been established in order to reduce the environmental contamination and exposure of PFASs. As a result, the analysis of PFAS is increasingly getting more important. For this purpose, we offer ready-to-use analytical solutions for successful PFAS analysis. We have created a landing page and video on this topic that will give you a overview about PFAS and PFAS analysis.
Vials and caps: MN website – your digital assistant
Nowadays we all can shop in webshops whenever it is convenient for us, but help and support are often limited to office hours. Experience all digital supporting tools on our website that assist you in your daily laboratory work, 24 hours a day, 7 days a week. Using the vials and caps product line as an example, we will show you all options our website offers to find out more about our products beyond the pure shopping world.
