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Genotyping and sequencing for genetic traits of companion animals and livestock

Genotyping and sequencing of genetic traits enables animal breeders to make knowledge-based breeding decisions to produce healthy offspring with the expected physical phenotype, therefore allowing for faster achievement of breeding goals. Understanding how genomics influences animal health, welfare, phenotype, and medical predispositions contributes to improved species-appropriate handling and to the development of new therapeutic drugs. 

MACHEREY-NAGEL offers specific products for reliable genomic DNA extraction from a diverse set of veterinary sample materials, allowing for more accurate downstream genetic analysis. 

  • Flexible solutions for a broad range of starting materials
  • Silica membrane (single spin, 8-well strips, 96-well plates) and magnetic bead-based options
  • Manual and automated processing Inhibitor-free nucleic acids suitable for all common downstream analysis assays (e.g. q(RT)-PCR, NGS)
  • Solutions for direct PCR genotyping
Purification of genomic DNA from cells and tissue

  • Silica membrane-based single spin kit 

NucleoSpin Tissue

  • Silica membrane-based 8-well strips

NucleoSpin 8 Tissue

  • Silica-membrane based 96-well plates

NucleoSpin 96 Tissue

  • Magnetic bead-based DNA isolation

NucleoMag Tissue

Purification of genomic DNA from blood

  • Silica membrane-based single spin ki

NucleoSpin Blood

  • Silica membrane-based 8-well strips

NucleoSpin 8 Blood

  • Silica-membrane based 96-well plates

NucleoSpin 96 Blood 

  • Magnetic bead-based DNA isolation 

NucleoMag Blood

Genomic DNA isolation from swabs

The magnetic bead-based NucleoMag DNA Swab kit allows the purification of genomic DNA from common swab types (e.g. cotton or synthetic flocked swabs) in a manual or automated format:

  • High throughput DNA isolation for genetic testing
  • Developed for cotton as well as synthetic swabs
  • Compatible with NucleoSpin Forensic Filters for convenient sample preparation

Product information about our solutions for RNA extraction, e.g. for transciptomic analysis, are not listed on this page. Please contact us for solutions for RNA extraction from your sample materials.

Please click here for more information on nucleic acid isolation for microbiome studies.

Automated sample extraction made easy!

Are you planning to automate your sample preparation? The automation specialists at MACHEREY-NAGEL can support you with implementing our kit solutions for nucleic acid extraction on your robotic platform. Contact us for automation support or for free and ready-to-go scripts, e.g. for the Thermo KingFisher or other magnetic rod and liquid handler platforms. 

E-Mail: bio-tech@mn-net.com I Tel.: +49 24 21 969 270

Direct PCR for genotyping

The NucleoType direct PCR products allow for rapid and reliable genotyping experiments without the requirement of DNA extraction or pretreatment of sample specimens:

Direct PCR from animal blood samples

The direct NucleoType Blood PCR kit is designed for rapid genotyping from whole blood (treated with EDTA, citrate, or heparin as anticoagulant) and blood dried on blood cards as sample material, without the need to purify DNA from blood: 

  • Blood Transfer Tool included
  • Inhibitor Removal Pearls for superior PCR results
  • Designed for human and animal blood samples
Direct PCR of tail, ear punches, and hair samples

The direct NucleoType Mouse PCR kit is designed for rapid mouse typing experiments with common samples such as tail clips, ear punches, and hair samples: 

  • DNA preparation within 5 minutes
  • Loading dye included for subsequent gel electrophoresis
  • Designed for tail, ear, blood and even hair samples