NucleoSpin technology

Rapid and easy preparation of DNA and RNA

Features

Chaotropic salt based silica membrane purification
Tailored purification systems for low (single columns), medium (8‑well strips) or high throughput (96‑well plates) approaches
Easy procedure from extra small (XS) to large scale (Maxi)

NucleoSpin principle

Binding

DNA / RNA is bound to the silica membrane under high salt conditions
Interaction between DNA / RNA (hydrate shell is reversibly removed by chaotropic salt) and silica membrane

Washing

Contaminants are washed away under high salt and / or ethanolic conditions to keep the DNA / RNA bound to the membrane

Elution

DNA / RNA is eluted in low salt buffer or water, DNA / RNA is ready to use for downstream applications