EC HPLC column (analytical), NUCLEODUR 100-5 CN-RP, 5 µm, 250x4.6 mm
The endcapped cyanopropyl phase is based on high purity NUCLEODUR silica gel. This HPLC phase is able to generate a clearly recognizable different retention behavior compared to purely alkyl-functionalized surface modifications. The polarity can be classified as intermediate based on multiple retention mechanisms such as dipole-dipole, π-π, and also hydrophobic interactions. Therefore, this phase shows a distinct selectivity for polar organic compounds as well as for molecules containing π electron systems (e.g., analytes with double bonds). Cyanopropyl HPLC columns can be run in the RP mode using aqueous-organic eluent mixtures as well as in the NP mode, e.g., with hexane as mobile phase.
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| Base material | NUCLEODUR - high purity silica |
|---|---|
| Brand | NUCLEODUR |
| Carbon content | 7.0 % |
| Column inner diameter | 4.6 mm |
| Column length | 250 mm |
| Column volume | 4.15 mL |
| Eluent in HPLC column | Acetonitrile – water |
| Endcapped | Yes |
| Gross weight (incl. packaging) | 282.2 g / 0.62 lbs |
| Hardware | Stainless steel |
| Hazardous material | No |
| Method | HPLC, analytical |
| Mode | Multi-mode (NP and RP), Reversed phase (RP) |
| Packaging dimensions | 400 x 115 x 54 mm / 15.75 x 4.53 x 2.13 Inch |
| Particle shape | Spherical |
| Particle size | 5 µm |
| Particle type | Fully porous particles (FPP) |
| pH stability | 1.0–8.0 |
| Phase | NUCLEODUR CN-RP 100-5 |
| Pore size | 110 Å |
| Pressure stability (max) | 600 bar / 8700 psi |
| Recommended application(s) | HPLC, NP applications, Normal phase, Organic acids, RP applications HPLC, Reversed phase, Steroids, Tricyclic antidepressants |
| Scope of delivery | 1x analytical HPLC column, instruction leaflet, certificate of analysis |
| Specific surface according to BET | 340 m²/g |
| Storage temperature | 15–25 °C / 59–77 °F |
| Surface chemistry | Cyano, nitrile (CN) modification |
| Temperature stability (max) | 60 °C |
| Type | EC HPLC column (analytical) |
| USP listing | L10 |
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