Editors
Instruction leaflet:
NUCLEOSIL®
RP columns


NUCLEOSIL® standard C18 phases
Octadecyl modified silica phases for HPLC
endcapped · USP L1
Features
Nonpolar, endcapped phases for RP chromatography
Available pore sizes 50, 100, 120, 300, 500 and 1000 Å
Available particle sizes 3 µm, 5 µm, 7 µm and 10 µm
pH stability at 20 °C: 2–8, carbon content depending on pore size (see table below)
Separation mechanism based on hydrophobic (van der Waals) interactions, slight residual silanol interactions
Corresponding NUCLEODUR® phases: see NUCLEODUR® C18 ec
For numerous applications click here.
Standard NUCLEOSIL® C18 phases are available as packed EC columns for analytical HPLC

EC standard columns for HPLC
Ordering information
Eluent in column acetonitrile – water
ID Length   EC guard
columns*

100 mm 125 mm 150 mm 250 mm
NUCLEOSIL® 50-5 C18 ec · 5 µm particles · 50 Å pores · 14.5 % C · endcapped    
4.6 mm       720098.46   721473.30
NUCLEOSIL® 100-3 C18 · 3 µm particles · 100 Å pores · 15 % C · endcapped    
4 mm   720150.40   720133.40   721022.30
4.6 mm 720841.46 720150.46 720949.46 720133.46   721022.30
NUCLEOSIL® 100-5 C18 · 5 µm particles · 100 Å pores · 15 % C · endcapped    
2 mm   720002.20
720014.20   721074.20
3 mm   720002.30
720014.30   721074.30
4 mm 720141.40 720002.40 720120.40 720014.40   721074.30
4.6 mm 720141.46 720002.46 720120.46 720014.46   721074.30
NUCLEOSIL® 100-7 C18 · 7 µm particles · 100 Å pores · 15 % C · endcapped    
4 mm       720018.40      
4.6 mm   720951.46 720110.46 720018.46      
NUCLEOSIL® 100-10 C18 · 10 µm particles · 100 Å pores · 15 % C · endcapped    
4 mm       720023.40      
4.6 mm   720701.46 720140.46 720023.46      
NUCLEOSIL® 120-3 C18 · 3 µm particles · 120 Å pores · 11 % C · endcapped    
4 mm 720149.40 720040.40   720055.40   721075.30
4.6 mm 720149.46 720040.46 720740.46 720055.46   721075.30
NUCLEOSIL® 120-5 C18 · 5 µm particles · 120 Å pores · 11 % C · endcapped    
4 mm   720051.40   720041.40   721070.30
4.6 mm   720051.46 720730.46 720041.46   721070.30
NUCLEOSIL® 120-7 C18 · 7 µm particles · 120 Å pores · 11 % C · endcapped    
4 mm       720042.40      
NUCLEOSIL® 120-10 C18 · 10 µm particles · 120 Å pores · 11 % C · endcapped    
4 mm       720043.40      
4.6 mm       720043.46      
NUCLEOSIL® 300-5 C18 · 5 µm particles · 300 Å pores · 6.5 % C · endcapped    
4 mm       720065.40   721085.30
4.6 mm       720065.46   721085.30
NUCLEOSIL® 500-7 C18 · 7 µm particles · 500 Å pores · 2 % C · endcapped    
4.6 mm       720074.46      
NUCLEOSIL® 1000-7 C18 · 7 µm particles · 1000 Å pores · ~ 1 % C · endcapped    
4.6 mm       720077.46      
Columns/pack -> 1 1 1 1   3
For EC columns with 2 mm ID 3 mm ID 4 mm ID 4.6 mm ID   REF
* EC guard columns EC 4/2 EC 4/3 EC 4/3 EC 4/3 use the Column Protection
System guard column holder
718966
Custom-packed EC columns with other dimensions are available on request.

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