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NucleoSpin® Bead Tubes
Our solution for RNA or DNA purification from hard to lyse sample materials
  
   

Since years MACHEREY-NAGEL is well known for expertise in purification of high quality RNA and DNA from a wide range of samples. Efficient lysis of starting material is crucial for obtaining desired amounts of highly pure RNA and DNA. Difficult to lyse sample materials are often associated with low yield of nucleic acids which and many scientists are faced with such situations nearly every day.

MN has now utilized its experience in RNA and DNA purification and has developed several NucleoSpin® Bead Tubes for efficient sample homogenization. These NucleoSpin® Bead Tubes are provided in different variants (e.g., glass beads, corundum, steel beads) appropriate to the respective application and/or sample material.
For example, the NucleoSpin® Bead Tubes Type A are recommended for homogenizing soil and sediments. Together with NucleoSpin® Bead Tubes Type G , being highly efficient in disrupting plant material, these bead tubes are very interesting for scientists working on metagenomic studies. The NucleoSpin® Bead Tubes Type B and C are of use for researchers working on microbiome analysis as these tubes can be used for the lysis of microbial organisms. NucleoSpin® Bead Tubes Type F are intended for clinical samples, especially for difficult to lyse tissue samples such as spleen or lung material. Even for insects, a special NucleoSpin® Bead Tube Type D is available.

NucleoSpin® Bead Tubes Type A and NucleoSpin® Bead Tubes Type A 5 mL can be combined with NucleoMag® DNA/RNA Water for optimal homogenization of waters and air filters. 

The NucleoSpin® Bead Tubes are already included in specific kits for RNA or DNA purification depending on the application. MN provides e.g., the NucleoSpin® DNA Insect kits with NucleoSpin® Bead Tubes Type D or the NucleoSpin® RNA Stool kit with NucleoSpin® Bead Tube Type A.

The NucleoSpin® Bead Tubes can be used with common bead mills (for details see NucleoSpin® Bead Tubes user manual). In addition, to faciliate easy disruption on a Vortex-Genie® 2, we provide the MN Bead Tube Holder and MN Bead Tube Holder 5 mL for 2 mL bead tubes and 5 mL bead tubes, respectively.

 

2 mL bead tubes
Product Specification To be used with In conjunction with   REF
NucleoSpin® Bead Tubes Type A 0.6-0.8 mm ceramic beads, for homogenization of soil, sediments, and stool NucleoSpin® Soil, NucleoSpin® Stool, NucleoBond® RNA Soil, NucleoSpin® RNA Stool 
(included), NucleoMag® DNA/RNA Water (optional)
MN Bead Tube Holder or mixer mill*  740786.50

NucleoSpin® Bead Tubes Type B

40-400 µm glass beads, for homogenization of Gram-positive and Gram-negative bacteria NucleoSpin® Microbial (included) MN Bead Tube Holder or mixer mill*  740812.50
NucleoSpin® Bead Tubes Type C 1-3 mm corundum,
for homogenization of yeast and fungi
NucleoSpin® Microbial (included) MN Bead Tube Holder or mixer mill*  740813.50

NucleoSpin® Bead Tubes Type D

3 mm steel beads,
for homogenization of insects, crustaceans, lipid-rich tissue
NucleoSpin® DNA Insect, NucleoSpin® DNA Lipid Tissue (included) MN Bead Tube Holder or mixer mill*  740814.50

NucleoSpin® Bead Tubes Type E

3 mm steel beads and 40–400 μm glass beads,
for homogenization of bacteria within insects or tissue samples

NucleoSpin® DNA Insect, NucleoSpin® DNA Lipid Tissue (optional) MN Bead Tube Holder or mixer mill*  740815.50
NucleoSpin® Bead Tubes Type F

1-3 mm corundum and 3 mm steel beads,
for homogenization of challenging tissues, e.g., spleen, or lung tissue

NucleoSpin® DNA RapidLyse (optional) MN Bead Tube Holder only! 740816.50
NucleoSpin® Bead Tubes Type G

5 mm steel beads,
for homogenization of plant material

NucleoSpin® RNA Plant and Fungi (optional) Mixer mill* 740817.50

5 mL bead tubes

Product Specification To be used with In conjunction with REF
NucleoSpin® Bead Tubes Type A 5 mL

0.6-0.8 mm ceramic beads, for homogenization of round filters (optional)

NucleoMag® DNA/RNA Water (optional) MN Bead Tube Holder 5 mL only! 740799.50

Accessories

Product Specification   REF
MN Bead Tube Holder to house up to 12 x 2 mL bead tubes in combination with a Vortex-Genie® instrument 740469
MN Bead Tube Holder 5 mL to house up to 8 x 5 mL bead tubes in combination with a Vortex-Genie® instrument 740459

*If using a bead mill, respect warnings, in the NucleoSpin® Bead Tubes user manual!

 

 

 

  
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