NucleoSpin® DNA Plasma Midi Circulating DNA from plasma
Isolation of cell-free DNA from up to 5 mL blood plasma

• Superior recovery of fragmented cell-free DNA
• Parallel purification of 24 samples – special adapter set for NucleoVac 96 Vacuum Manifold
• Optimized protocol for Cell-Free DNA BCT® ('Streck Tubes')**

Technology Silica-membrane technology
Format Midi spin columns
Sample material

1–5 mL plasma

Blood draw tubes EDTA, Cell-Free DNA BCT® (Streck)
Fragment size ≥ 50 bp
Typical yield Depending on sample source, storage, and quality
Elution volume 200 µL (140 µL final eluate volume)
Preparation time 90 min/24 preps (EDTA plasma)

• Typical downstream applications: NGS, qPCR, ddPCR
• Highly efficient recovery of cell-free DNA from 'Liquid Biopsies'

* Kits to be used for research purposes only
** Cell-free DNA BCT® is a registered trademark of Streck, Inc.



Ordering information



Specification REF
NucleoSpin® DNA Plasma Midi


NucleoSpin® Plasma Midi Columns, Collection Tubes, buffers, Proteinase K, Lysis Blocks 740303.48
NucleoSpin® DNA Plasma Midi Core Kit


NucleoSpin® Plasma Midi Columns, Collection Tubes, buffers, Proteinase K 740302.48
Product accessories Pack of Specification REF
NucleoVac 96 Vacuum Manifold 1 740681
NucleoVac Vacuum Regulator 1 for controlling of vacuum 740641
Starter Set Midi 1 set

for processing NucleoSpin® DNA Plasma Midi under vacuum on NucleoVac 96 Vacuum Manifold or similar manifolds; contains 1 Column Holder Midi, 1 Wash Plate Midi, 1 Elution Tube Holder Midi, and Dummy Columns


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