User manual 
NucleoSpin®  DNA FFPE XS

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NucleoSpin® DNA FFPE XS

NucleoSpin® DNA FFPE XS

Genomic DNA from FFPE sample

Previously known as NucleoSpin® FFPE DNA
Improved DNA quality from formalin-fixed, paraffin-embedded samples – no xylene needed

• Very easy paraffin removal – Paraffin Dissolver (patented technology) included
• Concentrated DNA by elution in small volume
• Overcoming formalin crosslinking of DNA by incubation in decrosslinking buffer
• High quality DNA for improved performance in PCR
Technology Silica-membrane technology
Format Mini spin columns – XS design
Sample material

≤ 7 sections (10 µm) of 250 mm2 total area (< 15 mg paraffin*)

Typical yield Depending on amount and quality of the sample
DNA quality Strongly depending on sample quality
Elution volume 5–30 µL
Preparation time 70 min/6 preps (excl. lysis)
Binding capacity 50 µg
• Rapid isolation of DNA from formalin-fixed, paraffin-embedded samples
• Isolation of DNA from fresh and archived FFPE samples
• Isolation of DNA from specimen of object slides
• Typical downstream application: PCR
* When using the standard protocol with Paraffin Dissolver. Larger quantities of paraffin can be processed when using additional Paraffin Dissolver or the protocol with xylene for deparaffinization.
** Kits to be used for research purposes only


Ordering information



Specification REF
NucleoSpin® DNA FFPE XS


NucleoSpin® DNA FFPE XS Columns, Collection Tubes (2 mL), Paraffin Dissolver, buffers, Proteinase K



as above 740980.50


as above 740980.250

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