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Separation of pain killers

Method:
Matrix
Application-No.:
TLC
402940

Substances: tolmetin; acetylsalicylic acid; diclofenac; naproxen; ibuprofen
Plate: ADAMANT® UV 254, 20 x 20 cm
Phase: ADAMANT
MN catalog number: 821030
Sample pretreatment:
Conditions: applied volume: 1 μl
eluent: chlorofom/acetic acid ethylester (1:1 v/v)
development: 20 min.
Detection
Subsequent analysis:
UV 254 nm

Author(-s): MACHEREY-NAGEL
Source: TLC department

Keywords: pain killers; drugs
Chromatogram:



Legend:

Substance

Concentration (%)

Rf

Tolmetin

1.0

0.05

Acetylsalicylic acid

2.0

0.12

Diclofenac

0.5

0.27

Naproxen

0.5

0.37

Ibuprofen

1.0

0.57

Distance in mm

 

70




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