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back to NUCLEODUR phase summary
NUCLEODUR
®
CN / CN-RP
high purity silica phase for HPLC
cyano (nitrile) modification for NP and RP separations
7 % C ·
USP L10
Features
pore size 110 Å, available particle sizes 3 µm and 5 µm
multi-mode columns (RP and NP)
widens the scope in selectivity
different retention characteristics in comparison to octadecyl and octyl modifications
stable against hydrolysis at low pH, working range pH 1 - 8
high reproducibility from lot to lot
separation mechanism based on π-π interactions, polar interactions (H bonds), and hydrophobic interactions
classes of compounds separated so far: tricyclic antidepressants, steroids, organic acids
Standard programme* of columns packed with NUCLEODUR
®
CN / CN-RP
Column system
Particle size:
3 µm
5 µm
5 µm
Eluent in column
CH
3
CN/H
2
O
CH
3
CN/H
2
O
n
-heptane
analytical
EC columns (standard system)
if you do not know our HPLC column systems, click the "i" for further information
* Please note! Most combinations of MN column types, available dimensions and particle sizes can be custom-packed on request.
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