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NUCLEODUR® high purity silica phases for HPLC
Features

NUCLEODUR® is a fully synthetical type B silica (silica of 3rd generation) offering highly advanced physical properties:
totally spherical particle shape
outstanding surface microstructure
high pressure stability
low metal content
NUCLEODUR® as a state-of-the-art silica is the ideal base material for modern HPLC phases. It is the result of MACHEREY-NAGEL's pioneering research in chromatography for more than 40 years.
NUCLEODUR® with 1.8 µm particle size for increased separation efficiency  


Summary of available NUCLEODUR® phases

Phase Modification % C pH range Particle sizes [µm] USP Structure
C18 Gravity octadecyl, high density coating, multi-endcapping 18 1 – 11 1.8 · 3 · 5 L1
C8 Gravity octyl, high density coating, multi-endcapping 11 1 – 11 1.8 · 5 L7
C18 Isis octadecyl, specially cross-linked modification, endcapped 20 1 – 10 1.8 · 3 · 5 L1
C18 Pyramid octadecyl with polar endcapping 14 1 – 9 1.8 · 3 · 5 L1
Sphinx RP bifunctional, balanced ratio of propylphenyl and octadecyl, endcapping 15 1 – 10 1.8 · 3 · 5 L1 L11
C18 HTec octadecyl, high density coating, high capacity, multi-endcapping 18 1 – 11 5 · 7 · 10 L1
C18 ec octadecyl, medium density, endcapping 17.5 1 – 9 3 · 5
and larger 		L1
C8 ec octyl, medium density, endcapping 10.5 1 – 9 3 · 5 L7
HILIC ammonium – sulphonic acid 7 2 – 8.5 1.8 · 3 · 5  
CN/CN-RP cyano (nitrile) for NP and RP separations 7 1 – 8 3 · 5 L10
NH2/NH2-RP aminopropyl for NP and RP separations 2.5 2 – 8 3 L8
SiOH unmodified NUCLEODUR® –   3 · 5
and larger		 L3

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