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| NUCLEODUR® high purity silica phases for HPLC |
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Features
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NUCLEODUR® is a fully synthetical type B silica (silica of 3rd generation) offering highly advanced physical properties:
- totally spherical particle shape
- outstanding surface microstructure
- high pressure stability
- low metal content.
NUCLEODUR® as a state-of-the-art silica is the ideal base material for modern HPLC phases. It is the result of MACHEREY-NAGEL's pioneering research in chromatography for more than 40 years.
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NUCLEODUR® with 1.8 µm particle size for increased separation efficiency
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Summary of available NUCLEODUR® phases
| Phase |
Modification |
% C |
pH range |
Particle sizes [µm]
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USP
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Structure |
C18 Gravity
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octadecyl, high density coating, multi-endcapping
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18 |
1 – 11
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1.8 · 3 · 5 |
L1
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C8 Gravity
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octyl, high density coating, multi-endcapping
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11 |
1 – 11 |
1.8 · 5 |
L7 |
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C18 Isis
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octadecyl, specially cross-linked modification, endcapped
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20 |
1 – 10 |
1.8 · 3 · 5 |
L1 |
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C18 Pyramid
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octadecyl with polar endcapping |
14 |
1 – 9 |
1.8 · 3 · 5 |
L1 |
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Sphinx RP
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bifunctional, balanced ratio of propylphenyl and octadecyl, endcapping
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15 |
1 – 10 |
1.8 · 3 · 5 |
L1 L11 |
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CN/CN-RP
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cyano (nitrile) for NP and RP separations
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7 |
1 – 8 |
3 · 5 |
L10 |
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NH2/NH2-RP
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aminopropyl for NP and RP separations
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2.5
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2 – 8
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3
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L8
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C18 ec
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octadecyl, medium density, endcapping
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17.5
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1 – 9 |
3 · 5
and larger |
L1 |
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C8 ec
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octyl, medium density, endcapping
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10.5 |
1 – 9 |
3 · 5 |
L7 |
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unmodified NUCLEODUR
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· / ·
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–
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3 · 5
and larger |
L3
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