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HPLC columns for enantiomer separation
Summary
Separation mechanism Phase Matrix / Modification
Polar and π-π interactions NUCLEOCEL Silica-based modified cellulose phases
Formation of inclusion complexes NUCLEODEX Silica-based permethylated and underivatized cyclodextrin phases
Ligand exchange NUCLEOSIL CHIRAL-1 Amino acid – Cu(II) complexes covalently bonded to sillica
Charge-transfer, dipole-dipole interactions and others NUCLEOSIL CHIRAL-2 / 3 Silica-based brush type phases
Enantioselective binding to chiral protein surface structures RESOLVOSIL BSA-7 Silica-based protein phase (BSA)
     

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