NUCLEOSIL C18

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back to NUCLEOSIL® phase summary

Instruction leaflet:
NUCLEOSIL®
RP columns

NUCLEOSIL® standard C18 phases
Octadecyl modified silica phases for HPLC
endcapped · USP L1

Features
	Nonpolar, endcapped phases for RP chromatography Available pore sizes 50, 100, 120, 300, 500, 1000 and 4000 Å Available particle sizes 3 µm, 5 µm, 7 µm and 10 µm pH stability at 20 °C: 2–8, carbon content depending on pore size (see table below) Separation mechanism based on hydrophobic (van der Waals) interactions, slight residual silanol interactions Corresponding NUCLEODUR® phases: see NUCLEODUR® C18 ec
	For numerous applications click here.
	Standard NUCLEOSIL® C18 phases are available as: Packed EC columns for analytical HPLC Packed VP columns for preparative HPLC

EC standard columns for HPLC
Ordering information
Eluent in column acetonitrile – water

Length

EC guard
columns*

CC guard
columns**

100 mm

125 mm

150 mm

250 mm

NUCLEOSIL® 50-5 C18 ec · 5 µm particles · 50 Å pores · 14.5 % C · endcapped

4.6 mm

720098.46

721473.30

721829.40

NUCLEOSIL® 100-3 C18 · 3 µm particles · 100 Å pores · 15 % C · endcapped

4 mm

720150.40

720133.40

721022.30

721866.40

4.6 mm

720841.46

720150.46

720949.46

720133.46

721022.30

721866.40

NUCLEOSIL® 100-5 C18 · 5 µm particles · 100 Å pores · 15 % C · endcapped

2 mm

720002.20

720120.20

720014.20

721074.20

721602.30

3 mm

720002.30

720120.30

720014.30

721074.30

721602.30

4 mm

720141.40

720002.40

720120.40

720014.40

721074.30

721602.40

4.6 mm

720141.46

720002.46

720120.46

720014.46

721074.30

721602.40

NUCLEOSIL® 100-7 C18 · 7 µm particles · 100 Å pores · 15 % C · endcapped

4 mm

720018.40

4.6 mm

720951.46

720110.46

720018.46

NUCLEOSIL® 100-10 C18 · 10 µm particles · 100 Å pores · 15 % C · endcapped

4 mm

720023.40

4.6 mm

720701.46

720140.46

720023.46

NUCLEOSIL® 120-3 C18 · 3 µm particles · 120 Å pores · 11 % C · endcapped

4 mm

720149.40

720040.40

720055.40

721075.30

721606.40

4.6 mm

720149.46

720040.46

720740.46

720055.46

721075.30

721606.40

NUCLEOSIL® 120-5 C18 · 5 µm particles · 120 Å pores · 11 % C · endcapped

4 mm

720051.40

720041.40

721070.30

721783.40

4.6 mm

720051.46

720730.46

720041.46

721070.30

721783.40

NUCLEOSIL® 120-7 C18 · 7 µm particles · 120 Å pores · 11 % C · endcapped

4 mm

720042.40

NUCLEOSIL® 120-10 C18 · 10 µm particles · 120 Å pores · 11 % C · endcapped

4 mm

720043.40

4.6 mm

720043.46

NUCLEOSIL® 300-5 C18 · 5 µm particles · 300 Å pores · 6.5 % C · endcapped

4 mm

720065.40

721085.30

721608.40

4.6 mm

720065.46

721085.30

721608.40

NUCLEOSIL® 500-7 C18 · 7 µm particles · 500 Å pores · 2 % C · endcapped

4.6 mm

720074.46

NUCLEOSIL® 1000-7 C18 · 7 µm particles · 1000 Å pores · ~ 1 % C · endcapped

4.6 mm

720077.46

NUCLEOSIL® 4000-7 C18 · 7 µm particles · 4000 Å pores · < 1 % C · endcapped

4.6 mm

720085.46

Columns/pack ->

For EC columns with	2 mm ID	3 mm ID	4 mm ID	4.6 mm ID		REF
* EC guard columns	EC 4/2	EC 4/3	EC 4/3	EC 4/3	use the Column Protection System guard column holder	718966
** CC guard columns	CC 8/3	CC 8/3	CC 8/4	CC 8/4	use the guard column adapter EC	721359

Custom-packed EC columns with other dimensions are available on request.

VarioPrep columns for preparative HPLC
Ordering information
Eluent in column acetonitrile – water

Length	8 mm ID	10 mm ID	16 mm ID	21 mm ID
NUCLEOSIL® 100-5 C18 · particle size 5 µm, pore size 100 Å · 15 % C · endcapped
250 mm		715340.100		715340.210
NUCLEOSIL® 100-7 C18 · particle size 7 µm, pore size 100 Å · 15 % C · endcapped
250 mm	715332.80	715332.100	715332.160	715332.210
NUCLEOSIL® 300-7 C18 · particle size 7 µm, pore size 300 Å · 6.5 % C · endcapped
250 mm		715806.100		715806.210
Guard columns with NUCLEOSIL® C18
	8 mm ID		16 mm ID
10 mm *	715360.80		715360.160
* 10 x 8 mm ID guard column cartridges can be used for 8 and 10 mm ID VarioPrep columns and require the guard column holder 8 mm (REF 718251), 10 x 16 ID guard column cartridges can be used for 16 and 21 mm ID VarioPrep columns and require the guard column holder 16 mm (REF 718256)
Custom-packed VP columns with other dimensions are available on request.
Other NUCLEOSIL® octadecyl phases than those listed above can also be custom-packed in VarioPrep columns.