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NUCLEOSIL® CN / CN-RP
cyano (nitrile) modified silica phases for HPLC · USP L10
Features

polar to mid-polar cyano (nitrile) modified silica for reversed phase and normal phase chromatography:
normal phase: with low-polarity solvents for many compounds, which can also be separated on unmodified silica, however, due to the rapid equilibration much more suitable for gradient separations
reversed phase: with different selectivity than C18, C8 or phenyl modified packings
available pore sizes 100, 120, 300 and 500 Å, available particle sizes 5 µm, 7 µm and 10 µm
separation mechanism based on π–π interactions, polar interactions and hydrophobic interactions
pH stability at 20 °C: 2 – 8
Please note! Eluent in column (except with NUCLEOSIL® 100-5 CN-RP) is n-heptane. When using an eluent which is not miscible with n-heptane (e. g. water), it is necessary to rinse the column with THF first.
for applications on NUCLEOSIL® CN phases klick here:


EC standard columns for analytical HPLC
Ordering information

ID Particle size Pore size Length ->     250 mm Guard columns*  
NUCLEOSIL® 100-5 CN (eluent in columns n-heptane)
4 mm 5 µm 100 Å       720090.40 721604.40  
4.6 mm 5 µm 100 Å       720090.46 721604.40  
NUCLEOSIL® 100-5 CN-RP (eluent in columns acetonitrile / water)
4 mm 5 µm 100 Å       720205.40 721917.40  
4.6 mm 5 µm 100 Å       720205.46 721917.40  
NUCLEOSIL® 100-10 CN (eluent in columns n-heptane)
4 mm 10 µm 100 Å       720024.40    
4.6 mm 10 µm 100 Å       720024.46    
NUCLEOSIL® 120-7 CN (eluent in columns n-heptane)
4 mm 7 µm 120 Å       720057.40    
4.6 mm 7 µm 120 Å       720057.46    
      Columns/pack     1 3  
* Guard column cartridges are coupled to EC columns using guard column adaptor EC (REF 721359).
4 mm ID (.40) CC guard column cartridges are applied for 4 and 4.6 mm ID EC columns.
Custom-packed EC columns with other dimensions are available on request.


NUCLEOSIL® CN bulk packings

Ordering information

Phase   Carbon content Pore size Particle Size Pack of 10 g Pack of 100 g
NUCLEOSIL 100-5 CN   5 % 100 Å 5 µm 712160.10 712160.100
NUCLEOSIL 100-10 CN   5 % 100 Å 10 µm 712170.10 712170.100
NUCLEOSIL 120-7 CN   ~ 3 % 120 Å 7 µm 712600.10 712600.100
NUCLEOSIL 300-7 CN   ~ 2.5 % 300 Å 7 µm 712820.10 712820.100
NUCLEOSIL 500-7 CN   ~ 2 % 500 Å 7 µm 712840.10 712840.100


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