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NUCLEOSIL® CN / CN-RP
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cyano (nitrile) modified silica phases for HPLC · USP L10
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polar to mid-polar cyano (nitrile) modified silica for reversed phase and normal phase chromatography:
normal phase: with low-polarity solvents for many compounds, which can also be separated on unmodified silica, however, due to the rapid equilibration much more suitable for gradient separations
reversed phase: with different selectivity than C18, C8 or phenyl modified packings
available pore sizes 100, 120, 300 and 500 Å, available particle sizes 5 µm, 7 µm and 10 µm
separation mechanism based on π–π interactions, polar interactions and hydrophobic interactions
pH stability at 20 °C: 2 – 8
Please note! Eluent in column (except with NUCLEOSIL® 100-5 CN-RP) is n-heptane. When using an eluent which is not miscible with n-heptane (e. g. water), it is necessary to rinse the column with THF first.
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for applications on NUCLEOSIL® CN phases klick here: 
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Standard programme* of columns packed with NUCLEOSIL® CN phases
Column system
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Particle
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Pore size [Å]
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100
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100
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120
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Eluent in column: |
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CH3CN/H2O
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n-heptane
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n-heptane |
analytical
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EC columns (standard system)
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5 µm
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7 µm
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10 µm
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ChromCart cartridge columns (CC)
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5 µm
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| if you do not know our HPLC column systems, click the "i" for further information |
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| * Please note! Most combinations of MN column types, available
dimensions and phases can be custom-packed on request. |
Programme of NUCLEOSIL® CN bulk packings
Particle size
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Pore size [Å]
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100
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120
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300
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500
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5 µm
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7 µm
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10 µm
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For ordering information click here 
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