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| NUCLEOSIL® CN / CN-RP |
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| cyano (nitrile) modified silica phases for HPLC · USP L10 |
| Features |
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polar to mid-polar cyano (nitrile) modified silica for reversed phase and normal phase chromatography:
normal phase: with low-polarity solvents for many compounds, which can also be separated on unmodified silica, however, due to the rapid equilibration much more suitable for gradient separations
reversed phase: with different selectivity than C18, C8 or phenyl modified packings
available pore sizes 100, 120, 300 and 500 Å, available particle sizes 5 µm, 7 µm and 10 µm
separation mechanism based on π–π interactions, polar interactions and hydrophobic interactions
pH stability at 20 °C: 2 – 8
Please note! Eluent in column (except with NUCLEOSIL® 100-5 CN-RP) is n-heptane. When using an eluent which is not miscible with n-heptane (e. g. water), it is necessary to rinse the column with THF first. |
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for applications on NUCLEOSIL® CN phases klick here:  |
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EC standard columns for analytical HPLC |
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| Ordering information |
| ID |
Particle size |
Pore size |
Length -> |
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250 mm |
Guard columns* |
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| NUCLEOSIL® 100-5 CN (eluent in columns n-heptane) |
| 4 mm |
5 µm |
100 Å |
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720090.40 |
721604.40 |
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| 4.6 mm |
5 µm |
100 Å |
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720090.46 |
721604.40 |
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| NUCLEOSIL® 100-5 CN-RP (eluent in columns acetonitrile / water) |
| 4 mm |
5 µm |
100 Å |
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720205.40 |
721917.40 |
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| 4.6 mm |
5 µm |
100 Å |
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720205.46 |
721917.40 |
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| NUCLEOSIL® 100-10 CN (eluent in columns n-heptane) |
| 4 mm |
10 µm |
100 Å |
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720024.40 |
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| 4.6 mm |
10 µm |
100 Å |
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720024.46 |
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| NUCLEOSIL® 120-7 CN (eluent in columns n-heptane) |
| 4 mm |
7 µm |
120 Å |
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720057.40 |
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| 4.6 mm |
7 µm |
120 Å |
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720057.46 |
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Columns/pack |
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1 |
3 |
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* Guard column cartridges are coupled to EC columns using guard column adaptor EC (REF 721359).
4 mm ID (.40) CC guard column cartridges are applied for 4 and 4.6 mm ID EC columns. |
| Custom-packed EC columns with other dimensions are available on request. |
NUCLEOSIL® CN bulk packings
Ordering information
| Phase |
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Carbon content |
Pore size |
Particle Size |
Pack of 10 g |
Pack of 100 g |
| NUCLEOSIL 100-5 CN |
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5 % |
100 Å |
5 µm |
712160.10 |
712160.100 |
| NUCLEOSIL 100-10 CN |
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5 % |
100 Å |
10 µm |
712170.10 |
712170.100 |
| NUCLEOSIL 120-7 CN |
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~ 3 % |
120 Å |
7 µm |
712600.10 |
712600.100 |
| NUCLEOSIL 300-7 CN |
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~ 2.5 % |
300 Å |
7 µm |
712820.10 |
712820.100 |
| NUCLEOSIL 500-7 CN |
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~ 2 % |
500 Å |
7 µm |
712840.10 |
712840.100 |
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