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NUCLEOSIL® standard silica phases for HPLC

Features

NUCLEOSIL® is a family of totally porous spherical silicas with a very pure and uniform SiO2 structure
wide acceptance as routine packings for very different fields of chromatography
one of the first spherical silicas used in HPLC
developed in the early seventies, it became a world-renowned HPLC packing
still found in many analytical and preparative applications
an absolutely reliable choice in HPLC
the largest variety of modified HPLC silicas available on the market


Summary of available NUCLEOSIL® phases
Phase Modification Formula
RP phases
NUCLEOSIL® C18 medium density octadecyl, endcapped -(CH2)17-CH3
NUCLEOSIL® C18 AB crosslinked octadecyl, endcapped, high steric selectivity -(CH2)17-CH3
NUCLEOSIL® C18 HD high density octadecyl, endcapped -(CH2)17-CH3
NUCLEOSIL® C18 Nautilus hydrophilic octadecyl, embedded polar group, endcapped -(CH2)17-CH3
NUCLEOSIL® Protect I special RP phase with protective polar group, endcapped
NUCLEOSIL® C8ec medium density octyl, endcapped -(CH2)7-CH3
NUCLEOSIL® C8 standard octyl, not endcapped -(CH2)7-CH3
NUCLEOSIL® C8 HD high density octyl, endcapped -(CH2)7-CH3
NUCLEOSIL® C4 medium density butyl, endcapped -(CH2)3-CH3
NUCLEOSIL® C2 dimethyl -(CH3)2
NUCLEOSIL® C6H5 ec medium density phenyl, endcapped -(CH2)3-C6H5
NUCLEOSIL® C6H5 standard phenyl, not endcapped -(CH2)3-C6H5
Polar phases
NUCLEOSIL® CN cyanopropyl (nitrile) -(CH2)3-CN
NUCLEOSIL® NO2 nitrophenyl -(CH2)3-C6H4-NO2
NUCLEOSIL® OH diol (dihydroxypropyl) -(CH2)3-O-CH2-CH(OH)-CH2OH
NUCLEOSIL® NH2 aminopropyl -(CH2)3-NH2
NUCLEOSIL® N(CH3)2 dimethylamino -(CH2)3-N(CH3)2
NUCLEOSIL® SA benzenesulphonic acid, strongly acidic cation exchanger (SCX) -(CH2)3-C6H4-SO3Na
NUCLEOSIL® SB quaternary ammonium, strongly basic anion exchanger (SAX) -(CH2)3-C6H4-CH2-N+(CH3)3Cl–
     
NUCLEOSIL® SiOH unmodified (SiO2)n

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