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Selection of CHROMABOND® phases for SPE

CHROMABOND® HR-Xpert
polymer RP and mixed-mode phases for acidic, basic and neutral compounds
Phases for water-soluble, non-ionic samples
Phases for water-soluble, ionic samples
Phases for samples soluble in organic solvents
Special phases for food, drug or environmental analysis
Products for phase separation or liquid-liquid extraction
SPE method development kits

Phase selection for water-soluble, non-ionic samples
Sample
solvent
Sample
polarity
Phases recommended for adsorption Solvents recommended for elution
(selection)
aqueous nonpolar RP phases HR-X, Easy, HR-P hexane, dichloromethane
      C18 ec, C18, C18 Hydra acetonitrile, alcohols
      C8, C4, C2  
      C6H11 ec, C6H5  
    NP phases CN trichloromethane, dichloromethane
aqueous moderately polar   SiOH ethyl acetate, alcohols, water
      NH2  
aqueous polar   CN, OH (Diol) as above
      NH2, HILIC  
         

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Phase selection for water-soluble, ionic samples
Sample
solvent
Sample
polarity
Phases recommended for adsorption Solvents recommended for elution
(selection)
aqueous cationic Ion exchange phases HR-XC, HR-XCW, PS-H+ acids, salt solutions, buffers
      SA, PCA, PSA  
aqueous anionic   HR-XA, HR-XAW, PS-OH acids, salt solutions, buffers
      SB  
    NP phases NH2  
         

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Phase selection for samples soluble in organic solvents
Sample
solvent
Sample
polarity
Phases recommended for adsorption Solvents recommended for elution
(selection)
aqueous nonpolar RP phases HR-X, Easy, HR-P hexane, dichloromethane
      C18 ec, C18, C18 Hydra acetonitrile, alcohols
      C8, C4, C2  
      C6H11 ec, C6H5  
      PS-RP  
    NP phases CN chloroform, dichloromethane
organic moderately polar   SiOH ethyl acetate, alcohols, water
      NH2  
organic polar   CN, OH (Diol)
as above
      NH2, HILIC  
         

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