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How to select the optimal CHROMAFIL® syringe filter


1. Filter size
Sample volume
  5–100 mL

1–5 mL

< 1 mL

Filter size
  25 mm
13 mm
3 mm



2. Pore size of filter membrane
 
Pore size
For general purpose
HPLC columns packed with particles > 3 µm, GC, SFC, ...


0.45 µm


Recommended for
UHPLC-, core-shell and HPLC columns, packed with particles < 3 µm, GC, SFC, ...


0.20 µm




3. Membrane type
Properties of sample
Recommended Alternatives
Aqueous, polar, hydrophilic
low particle-load
high particle-load, prefiltration required

PET
GF/PET

H-PTFE, MV, RC
GF/RC, GF/PVDF
Mid-polar, e.g., HPLC eluents
low particle-load
high particle-load, prefiltration required

PET
GF/PET

PA
, RC
GF/PA
Contains proteins
low binding capacity of proteins
high binding capacity of proteins

CA
GF

PVDF, PES
GF/PVDF, GF/PET
Strongly acidic or basic
low particle-load
high particle-load, prefiltration required

H-PTFE
GF/PTFE

PTFE
GF
Organic, nonpolar, hydrophobic
low particle-load
high particle-load, prefiltration required

PTFE
GF/PTFE

PET
GF/PET, GF/PVDF
Aqueous, for ion chromatography
IC
 


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