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| NucleoMag® technology and products |
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| Features |
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Technology /
separation principle |
Magnetic-bead technology /
chaotropic salt binding |
| Material |
Superparamagnetic beads (non-silica) |
| Format |
Flexible |
| Procedure |
Principle: binding (high-salt) – washing – elution (low-salt)
• Adsorption of DNA / RNA in the presence of chaotropic salts
(hydrate shell of DNA / RNA is reversibly removed)
• High-salt / ethanolic washing steps to remove contaminants
• Low-salt or water elution (hydrate shell is recovered, DNA is released
from the beads) |
| Features/Result |
Highly-pure ready-to-use PCR products, genomic DNA, RNA
Easily adapted to automated use, e.g. on KingFisher®, KingFisher® mL,
KingFisher® 96, and KingFisher® Flex |
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| NucleoMag® principle |
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