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NucleoSpin® technology and products
Features
Technology /
separation principle
Silica-membrane technology /
chaotropic salt binding
Material

Silica membrane

Format Spin columns Low throughput systems, from extra small to extra large scale
8-well strips Medium-throughput systems,
for vacuum manifolds, centrifuges, and robotic systems
96-well plates High-throughput systems,
for vacuum manifolds, centrifuges, and robotic systems
Procedure Principle: binding (high-salt) – washing – elution (low-salt)

• Adsorption of DNA / RNA in the presence of chaotropic salts 
  (hydrate shell of DNA / RNA is reversibly removed)   
• High-salt / ethanolic washing steps to remove contaminants
• Low-salt or water elution 
  (hydrate shell is recovered, DNA/RNA is released from the membrane)
Features/Result Ready-to-use, sequencing and PCR-grade DNA / RNA
From extra small to extra large scale, from low to high throughput
No alcohol precipitation necessary
Fast and easy procedure
NucleoSpin® principle
 
  
     
Products
Plasmid DNA Purification
Plasmid DNA Purification
Plasmid Mini prep NucleoSpin® Plasmid / Plasmid (NoLid)
NucleoSpin® Plasmid EasyPure

Manual and automated high throughput (HTP) 
plasmid Mini prep

NucleoSpin® 8 Plasmid / Core Kit
NucleoSpin® 96 Plasmid / Core Kit
Clean-up
PCR clean-up, gel extraction
Single prep NucleoSpin® Gel and PCR Clean-up
Manual and automated high throughput (HTP) PCR clean-up NucleoSpin® 8 PCR Clean-up / Core Kit
NucleoSpin® 96 PCR Clean-up / Core Kit
Genomic DNA clean-up
Single prep NucleoSpin® gDNA Clean-up
Single prep NucleoSpin® gDNA Clean-up XS
RNA
RNA from cells and tissue
Single prep NucleoSpin® RNA
NucleoSpin® RNA Plus
NucleoSpin® RNA XS
NucleoSpin® RNA Midi

Manual and automated high throughput (HTP)

NucleoSpin® 8 RNA / Core Kit
NucleoSpin® 96 RNA / Core Kit
MicroRNA
Single prep NucleoSpin® miRNA
NucleoSpin® miRNA Plasma
RNA, DNA, and protein
Single prep NucleoSpin® TriPrep
NucleoSpin® RNA/Protein
NucleoSpin® RNA/DNA Buffer Set
RNA from blood
Single prep NucleoSpin® RNA Blood
NucleoSpin® RNA Blood Midi
Manual and automated high throughput (HTP) NucleoSpin® 8 RNA Blood
NucleoSpin® 96 RNA Blood
RNA from plant
Single prep NucleoSpin® RNA Plant
RNA from FFPE samples
Single prep NucleoSpin® totalRNA FFPE
NucleoSpin® totalRNA FFPE XS
RNA Clean-up
Single prep NucleoSpin® RNA Clean-up
NucleoSpin® RNA Clean-up XS
Genomic DNA
Circulating DNA from plasma
Single prep NucleoSpin® Plasma XS
NucleoSpin® DNA Plasma Midi
Manual and automated high throughput (HTP) NucleoSpin® 96 DNA Plasma
Genomic DNA from blood and biological fluids
Single prep NucleoSpin® Blood
NucleoSpin® Blood QuickPure
NucleoSpin® Blood L (Midi)
NucleoSpin® Blood L Vacuum (Midi)
NucleoSpin® Blood XL (Maxi)
NucleoSpin® Dx Blood (CE-IVD marked)
Manual and automated high throughput (HTP) NucleoSpin® 8 Blood QuickPure
NucleoSpin® 96 Blood QuickPure
NucleoSpin® 8 Blood / Core Kit
NucleoSpin® 96 Blood / Core Kit
Genomic DNA from tissue and cells
Single prep NucleoSpin® Tissue
NucleoSpin® Tissue XS
NucleoSpin® DNA Lipid Tissue
NucleoSpin® DNA Insect
Manual and automated high throughput (HTP) NucleoSpin® 8 Tissue / Core Kit
NucleoSpin® 96 Tissue / Core Kit
Genomic DNA from FFPE samples
Single prep NucleoSpin® DNA FFPE XS
Manual and automated HTP NucleoSpin® 96 DNA FFPE
Genomic DNA from forensic samples
Single prep NucleoSpin® DNA Trace
NucleoSpin® DNA Forensic
Manual and automated HTP NucleoSpin® 8 Trace
NucleoSpin® 96 Trace
Genomic DNA from plant and fungi
Single prep NucleoSpin® Plant II
NucleoSpin® Plant II Midi
NucleoSpin® Plant II Maxi
Manual and automated high throughput (HTP) NucleoSpin® 8 Plant II / Core Kit
NucleoSpin® 96 Plant II / Core Kit
Genomic DNA from microorganisms
Single prep NucleoSpin® Microbial DNA
Genomic DNA from soil and stool samples
Single prep NucleoSpin® Soil
NucleoSpin® DNA Stool
Manual and automated high throughput (HTP) NucleoSpin® 96 Soil
Genomic DNA from food and feed
Single prep NucleoSpin® Food
Manual and automated high throughput (HTP) NucleoSpin® 8 Food
NucleoSpin® 96 Food
Viral RNA and DNA
Viral RNA / DNA from serum and plasma
Single prep NucleoSpin® Virus
NucleoSpin® RNA Virus
NucleoSpin® Dx Virus (CE-IVD marked)
NucleoSpin® RNA Virus F
Manual and automated high throughput (HTP) NucleoSpin® 8 Virus / Core Kit
NucleoSpin® 96 Virus / Core Kit
Viral DNA from serum and plasma
Single prep NucleoSpin® Blood
 
  
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