Editors
Selection of CHROMABOND® phases for SPE

CHROMABOND® HR-Xpert
polymer RP and mixed-mode phases for acidic, basic and neutral compounds
Phases for water-soluble, non-ionic samples
Phases for water-soluble, ionic samples
Phases for samples soluble in organic solvents
Special phases for food, drug or environmental analysis
Products for phase separation or liquid-liquid extraction
SPE method development kits

Phase selection for water-soluble, non-ionic samples
Sample
solvent
Analyte
polarity
Phases recommended for adsorption Solvents recommended for elution
(selection)
aqueous

nonpolar

RP phases

HR-X, Easy, HR-P acetonitrile, alcohols,
trichloromethane, dichloromethane, hexane
      C18 ec, C18,
C18 Hydra


      C8, C4, C2,  
      C6H11 ec, C6H5, CN  
aqueous


nonpolar / moderately polar

HLB phase


HLB


for HPLC: methanol, acetonitrile
for GC: ethyl acetate, MTBE, dichloromethane (addition of 10 % methanol)
aqueous*
moderately polar
NP phases
SiOH
ethyl acetate, alcohols

    NH2  
aqueous polar   CN, OH (Diol) ethyl acetate, alcohols

    NH2, HILIC  
* with an addition of organic solvent for SiOH phase

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Phase selection for water-soluble, ionic samples
Sample
solvent
Analyte
polarity
Phases recommended for adsorption Solvents recommended for elution
(selection)
aqueous cationic Cation exchange phases HR-XC, HR-XCW, PS-H+, bases, also acids, salt solutions, buffers
      SA, PCA, PSA  
aqueous anionic Anion exchange phases HR-XA, HR-XAW, PS-OH, acids, also bases, salt solutions, buffers
      SB  
    NP phases NH2  
         

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Phase selection for samples soluble in organic solvents
Sample
solvent
Analyte
polarity
Phases recommended for adsorption Solvents recommended for elution
(selection)
organic nonpolar
RP phases
HR-X, Easy, HR-P hexane, dichloromethane, chloroform,
      C18 ec, C18, C18 Hydra acetonitrile, alcohols
      C8, C4, C2
      C6H11 ec, C6H5  
      PS-RP  
   
CN
organic moderately polar NP phases SiOH ethyl acetate, alcohols
      NH2  
organic polar   CN, OH (Diol)
chloroform, dichloromethane,
      NH2, HILIC ethyl acetate, alcohols
         

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